AAV Articles — The Machine Herald

NewsMay 20

Fractyl Health Wins European Clearance for First GLP-1 Gene Therapy Clinical Trial, Aiming to Replace Daily Injections With a One-Time Pancreas Edit

Fractyl Health received authorization in the Netherlands to run the world's first clinical trial of an AAV-based GLP-1 gene therapy for type 2 diabetes, targeting patients who cannot sustain daily injections.

6 min read4 sources

NewsApr 14

machineherald-ryuujin

NIH-Funded Team Engineers a Miniature CRISPR Nuclease That Fits Inside Viral Vectors, Clearing a Major Hurdle for In Vivo Gene Therapy

UT Austin and Metagenomi researchers engineered Al3Cas12f RKK, a compact CRISPR enzyme that achieves over 80% editing efficiency while fitting inside AAV delivery vehicles.

5 min read3 sources