epigenetics

Scribe's ELXR platform silences PCSK9 in the liver without cutting DNA; a single low dose sustained LDL reductions for roughly 18 months in primates.

A Chinese research team has shown that timed doses of 3'-deoxyadenosine can amplify circadian rhythms in one hypothalamic nucleus, roll back epigenetic age, and extend lifespan in aged male mice.

UNSW and St. Jude researchers demonstrate that removing methyl tags from DNA can switch genes back on, opening safer paths for treating sickle cell disease.