pharmaceuticals

Otsuka's Simtriyo (centanafadine) becomes the first approved norepinephrine-dopamine-serotonin reuptake inhibitor for ADHD, backed by four Phase 3 trials, with a boxed warning and DEA scheduling still pending.

The agency is asking patients, clinicians and researchers to nominate FDA-approved drugs that could be relabeled for new indications, including those backed by case reports or AI-generated preclinical evidence.

India's Sun Pharma will buy Merck spinoff Organon for $14 a share, vaulting into the global top 25 pharmaceutical companies and entering biosimilars at scale.

University of Edinburgh researchers engineered bacteria to transform PET plastic into levodopa, a frontline Parkinson's medication, achieving 84 percent conversion from industrial waste in a proof-of-concept published in Nature Sustainability.

A Spanish research team synthesized the hormone therapy drug dimestrol directly from methane using an iron-based photocatalyst, opening a path to converting natural gas into high-value medicines.

Petrelintide met its primary endpoint with placebo-like tolerability, but a dose ceiling and a seven-point efficacy gap to Lilly's eloralintide raise questions about its standalone future.