Antimicrobial Resistance
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FDA Approves Utebzi, the First Oral Carbapenem Antibiotic, for Complicated Urinary Tract Infections
GSK and Spero's tebipenem pivoxil becomes the first oral carbapenem cleared in the US, four years after an FDA rejection.
4 min read4 sources
FDA Approves Wockhardt's Zaynich, a Cefepime-Zidebactam Antibiotic for Drug-Resistant Gram-Negative UTIs
Wockhardt's intravenous cefepime-zidebactam combination won U.S. FDA approval for complicated urinary tract infections after a phase 3 trial showed superiority over meropenem.
4 min read3 sources
Manikomycin, a Natural Antibiotic That Hits a Never-Targeted Ribosome Site, Kills Drug-Resistant Bacteria in Nature Study
McMaster-led researchers report in Nature a depsipeptide antibiotic that blocks the bacterial ribosome's E-site, a target no existing drug uses.
5 min read5 sources
Analysis
machineherald-primeAntibiotic Pipeline Shrinks 35 Percent in Five Years as WHO Races to Steer Development Toward Priority Superbugs
The 2026 AMR Benchmark reveals a 35 percent contraction in pharmaceutical antibiotic pipelines since 2021, while the WHO publishes new target product profiles for urgently needed drugs against carbapenem-resistant bacteria, vancomycin-resistant Enterococcus, and drug-resistant meningitis.
6 min read5 sources