Biotech & Medicine
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Engineered E. Coli Converts Plastic Bottle Waste into Parkinson's Drug in Bioengineering First
University of Edinburgh researchers engineered bacteria to transform PET plastic into levodopa, a frontline Parkinson's medication, achieving 84 percent conversion from industrial waste in a proof-of-concept published in Nature Sustainability.
Epia Neuro Launches with a Minimally Invasive Brain-Computer Interface Designed to Restore Hand Function After Stroke
Epia Neuro emerged from stealth on April 2 with a read/write BCI platform that decodes neural intent and drives a grip-assist prosthetic, targeting first-in-human trials at Lenox Hill Hospital later this year.
First Phase III Trial to Combine a Microbiome Pill with Cancer Immunotherapy Enrolls Over 700 Kidney Cancer Patients
The SWOG S2419 BioFront study is the first large-scale randomized trial testing whether a daily oral bacterial supplement can boost immunotherapy outcomes in advanced kidney cancer.
Johns Hopkins Digital Twin Hearts Achieve 100% Arrhythmia-Free Rate in First FDA-Approved Clinical Trial
The TWIN-VT trial used personalized computational heart models to guide ventricular tachycardia ablation, with all 10 patients remaining arrhythmia-free after more than a year.
Cauldron Ferm Raises $13.25 Million to Scale Continuous Hyper-Fermentation Platform Beyond 10,000-Liter Demonstration
Australian biomanufacturing startup Cauldron Ferm has closed a $13.25 million Series A2 round to expand its continuous hyper-fermentation platform, which it claims reduces unit costs by up to 50 percent and capital expenditure by 45 percent compared to conventional batch processes.
Neuralink Demonstrates Thought-to-Speech in ALS Patient as VOICE Trial Begins Decoding Silent Neural Signals
Neuralink's VOICE trial decoded silent neural signals from an ALS patient's brain into synthesized speech as the company's BCI program scales to 21 participants worldwide.
Restoring a Single Brain Clock Reverses Aging Biomarkers and Extends Lifespan in Mice, Cell Study Finds
A Chinese research team has shown that timed doses of 3'-deoxyadenosine can amplify circadian rhythms in one hypothalamic nucleus, roll back epigenetic age, and extend lifespan in aged male mice.
Texas Commits $50 Million to Largest State-Funded Ibogaine Clinical Trial After Drug Companies Fail to Meet Partnership Terms
Texas will fully fund a $50 million ibogaine trial through 11 universities after no drug company met partnership terms, targeting PTSD, addiction, and TBI in veterans.
Envoy Medical Reports First Patients Reaching 12-Month Endpoint in Pivotal Trial of Fully Implanted Cochlear Implant
Three participants in the Acclaim cochlear implant trial have completed their primary 12-month evaluations, bringing the first fully implanted cochlear implant closer to FDA submission.
ARPA-H Awards $144 Million to Seven Teams Racing to Prove FDA-Approved Drugs Can Extend Human Healthspan
The US government's health research agency has funded the first large-scale clinical trials testing whether rapamycin, semaglutide, and other repurposed drugs can slow biological aging in healthy adults, with results expected within three years.
Butterfly Network Wins First FDA Clearance for a Blind-Sweep Ultrasound AI That Estimates Gestational Age Without a Trained Sonographer
The FDA has cleared Butterfly Network's Gestational Age Tool, the first blind-sweep ultrasound AI authorized for U.S. marketing, letting any healthcare worker estimate fetal age in under two minutes.
Stanford and Arc Institute Trace Age-Related Memory Loss to a Single Gut Bacterium, Then Reverse It via the Vagus Nerve
A Nature study identifies Parabacteroides goldsteinii as a driver of cognitive decline in aging mice and shows that stimulating the vagus nerve with GLP-1 receptor agonists restores memory to youthful levels.