Biotech & Medicine
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Xenon's Azetukalner Cuts Seizure Frequency by 53% in Phase 3 Trial, Poised for First-in-Class FDA Submission
Phase 3 data presented at AAN 2026 show azetukalner nearly halved seizure frequency in treatment-resistant focal epilepsy, with 38% of long-term patients achieving over a year of seizure freedom.
Northwestern Engineers Print Artificial Neurons That Talk to Living Brain Cells
Researchers at Northwestern University have used aerosol jet printing to create flexible artificial neurons that generate biologically realistic signals and directly activate living neural tissue.
Kent MenB Outbreak Triggers Second-Dose Push for Nearly 12,000 Exposed People
UK health officials are widening the MenB response in Kent by offering second doses to people already given a first shot, after an outbreak that has left two people dead and 21 confirmed cases.
Philips Wins FDA Clearance for Verida, the First Detector-Based Spectral CT With AI Baked Into the Reconstruction Chain
The Dutch medtech giant cleared a 510(k) for a spectral CT that reconstructs 145 images per second using a deep learning engine, bringing always-on spectral imaging to US hospitals for the first time.
Revolution Medicines' Daily Pill Daraxonrasib Nearly Doubles Survival in Metastatic Pancreatic Cancer, Cutting Risk of Death by 60 Percent
Phase 3 RASolute 302 data show the oral RAS inhibitor extending median overall survival to 13.2 months versus 6.7 months on chemotherapy, sending Revolution Medicines shares up nearly 40 percent.
Connectome-seq Turns Brain Wiring into a Sequencing Problem, Mapping Thousands of Synaptic Connections with RNA Barcodes
University of Illinois researchers publish Connectome-seq in Nature Methods, using RNA barcodes to map over 1,000 neurons at single-synapse resolution and uncover previously unknown connectivity patterns in the mouse brain.
Berkeley's Innovative Genomics Institute Uses CRISPR to Boost Sorghum Photosynthesis Gene Expression More Than 30-Fold
Two companion Nature Biotechnology papers map over 30,000 CRISPR edits across sorghum's regulatory DNA, achieving unprecedented control over photosynthesis genes with implications for crop yields and carbon capture.
NIH-Funded Team Engineers a Miniature CRISPR Nuclease That Fits Inside Viral Vectors, Clearing a Major Hurdle for In Vivo Gene Therapy
UT Austin and Metagenomi researchers engineered Al3Cas12f RKK, a compact CRISPR enzyme that achieves over 80% editing efficiency while fitting inside AAV delivery vehicles.
Scientists Discover a Hidden Lymphatic Drainage Hub in the Human Brain, Rewriting the Map of Cerebral Waste Clearance
MRI imaging and tissue analysis reveal that the middle meningeal artery hosts an organized lymphatic network responsible for brain waste removal, with implications for Alzheimer's research.
Fecal Transplant Capsules Nearly Double Immunotherapy Response Rates Across Three Cancer Types in Phase I/II Trials
Two companion trials published in Nature Medicine show oral FMT capsules raised immunotherapy response rates to 80% in lung cancer and 75% in melanoma, while reducing toxic side effects in kidney cancer.
Ascendis Pharma Launches YUVIWEL in the US, Bringing the First Weekly Injection for Achondroplasia to Market with Seven-Year Orphan Exclusivity
The first once-weekly treatment for achondroplasia is now commercially available in the United States after Ascendis Pharma secured orphan drug exclusivity through 2033.
Largest TB Vaccine Trial in Decades Finds VPM1002 Halves Extrapulmonary Risk but Falls Short of Broad Protection
Phase 3 PreVenTB trial of 12,717 people across India shows VPM1002 cuts extrapulmonary tuberculosis by 50%, but neither candidate prevents pulmonary TB or latent infection.